Postpartum depression . . . and other stories
BMJ 2023; 383 doi: https://doi.org/10.1136/bmj.p2825 (Published 07 December 2023) Cite this as: BMJ 2023;383:p2825
Genetics of postpartum depression
Despite data from 20 000 cases of postpartum depression and three times that number of controls, a meta-analysis of genetic association studies fails to identify a single-nucleotide polymorphism of genome-wide significance. This is something of a puzzle because twin studies have suggested that the condition has a heritability of more than 50%. The investigators say that larger studies are needed (Am J Psychiatry doi:10.1176/appi.ajp.20230053).
Mediterranean lifestyle
In the 1960s, Ancel Keys’ cross cultural comparisons showed that people living in Mediterranean countries experienced a low mortality from cardiovascular disease, and gave rise to the idea that a diet low in saturated fat and rich in vegetables is especially healthy. This seems to be true …
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