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Endgames Spot Diagnosis

A young boy with fever and red rash all over the body

BMJ 2025; 388 doi: https://doi.org/10.1136/bmj-2024-082484 (Published 06 March 2025) Cite this as: BMJ 2025;388:e082484
  1. Kun Huang, resident paediatrician1,
  2. Chunlin Wang, consultant paediatrician1
  1. 1Department of Pediatrics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
  1. Correspondence to: C Wang hzwangcl{at}zju.edu.cn

A child presented with a one week history of a painless non-pruritic erythematous rash. The rash initially appeared on his back, chest, and abdomen before it became widespread. Two days after the appearance of the rash, he developed fever with a maximum temperature of 39°C, accompanied by progression of the rash with coalescence over the trunk and limbs. In a local hospital, he was given three days of oral cefixime to treat a suspected respiratory infection. His fever persisted, with a temperature of 38-39°C, mainly at night. In addition, the rash on his limbs worsened, he coughed white sticky sputum, and had a mild sore throat. On examination, the rash was red, maculopapular, and blanching. It was densely distributed on the boy’s chest and abdomen (fig 1), back (fig 2), and lower limbs (fig 3). His tonsils were red and his tongue was bright red with prominent, white tipped papillae (fig 4).

Fig 1

Rash on the abdomen

Fig 2

Skin on the back with a texture of sandpaper

Fig 3

Rash on the right leg

Fig 4

“Strawberry tongue” and pallor around the mouth

Laboratory tests showed a normal white cell count (8.89×109/L, reference range 4-10×109/L), an increased C …

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