Should we sequence everyone’s genome? Yes

We should all have our genomes sequenced. In 1986 our 5 year old son planted a conker in our back yard. He explained that he wanted a tree house so needed a tree. The tree is now ready to receive boarders, though they will be from our family’s next generation. The Human Genome Project began at about the same time with similar high aspirations: to deliver personalised medicine to generations to come.

That time is now upon us. The cost of gene sequencing has fallen 10 000-fold in a decade, with another drop by an order of magnitude expected soon. Setting aside the considerable but surmountable challenges associated with large segments being duplicated or deleted and stretches of hard to sequence repeats, we can have a whole genome for the price of a family package holiday. Even now, bulk sequencing all 20 000 “genes,” the exome, costs less than £500 (€590; $770).

The Human Genome Project depended on British discovery, particularly the work of the Wellcome Trust’s Sanger Institute. No one can match our capacity to do “genetic medicine” in a …